How can we characterize the burden of post-acute sequelae of COVID-19 in the community? JohnsHopkins PASC COVID19 Coronavirus LongCOVID Burden SARSCoV2
By Tarun Sai LomteJan 3 2023Reviewed by Aimee Molineux In a recent study published in PLOS ONE, researchers characterized the burden of post-acute sequelae of coronavirus disease 2019 [PASC] in community-dwelling individuals.
About the study In the present study, researchers explored the experiences of PASC in a cohort of community-dwelling adult individuals who had COVID-19 by implementing a convergent mixed methods design. These methods involve the collection and analysis of qualitative and quantitative data. Qualitative interviews allowed for understanding the experiences of those at an elevated risk of severe COVID-19 and who had cardiovascular disease .
Self-administered surveys captured information on sociodemographic characteristics, SARS-CoV-2 testing, exposure, vaccination, and morbidities, such as CVD, hypertension, dyslipidemia, cancer, asthma, and kidney disease, among others. Individuals reporting PASC symptoms were older, more likely females, comorbid, and required hospitalization during COVID-19. 29% of participants reported having cardiovascular risk factors before COVID-19, and 77% reported PASC symptoms. Cardiac-related PASC was reported by 43% of participants, and 27% reported new-onset CV risk factors or CVD.
Several participants were frustrated due to the apparent invisibility and persistent debilitation of symptoms. In fact, the frustration appeared to stem from the desire to look sick so that their symptoms could be recognized. One interviewee indicated that PASC clinics were unhelpful and had to turn to other chronic care specialists.
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