HIV a culprit in more than half of Tuberculosis deaths in SouthAfrica ~
HIV has dramatically increased tuberculosis incidence and mortality in South Africa, according to the first study to assess the impact of HIV and multiple TB interventions on the country’s TB burden at a national level.
According to the findings, interventions implemented by the South African TB program have led to notable reductions in TB incidence, with ART and increased screening contributing to most of the decline. With HIV being the strongest driver of the TB epidemic, Kubjane says the model estimated that even in the absence of HIV, TB incidence in South Africa would remain high.
In 2019, the study found that the provision of ART led to a 20% reduction in TB incidence. “The benefits of ART in reducing incidence depend on CD4 count and duration of ART. HIV-positive individuals who initiate ART earlier at higher CD4 counts and stay on ART for longer experience the greatest benefits of ART,” says Kubjane.
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