People with high genetic stress sensitivity, as well as anxiety or depression, are at a much higher risk of heart attack during times of socio-political stress. Doctors explain.
Your genes could put you at a higher risk of heart attack during very stressful times. Research from Massachusetts General Hospital found that people who have specific genetic traits, paired with anxiety or depression, are at a 'significantly higher heart attack risk' during periods of social or political stress, such as presidential elections, winter holidays or even the Super Bowl.
These syndromes include heart attacks and other 'serious conditions where the heart is suddenly deprived of blood supply,' a press release noted. Of 18,428 Mass General Brigham Biobank participants, 1,890 developed ACS between 2000 and 2020. The researchers measured the participants' stress sensitivity by measuring their neuroticism polygenic risk score . Stressful periods — including five days after presidential elections and 10 days surrounding Christmas Day — made up 3.
People with high genetic stress sensitivity had a 36% higher risk of ACS, the researchers found. Those with high genetic stress who also developed anxiety or depression had three times the risk. 'High nPRS, indicating elevated genetic susceptibility to stress, mediates ACS risk during periods of socio-political stress,' the study authors wrote as a conclusion. 'A multifaceted approach to prevention may benefit.
So, if you have both conditions, you would expect to have a substantial increase in your risk,' he said. Through scientific analysis, Abohashem and his fellow researchers found that about 25% of ACS cases were due to anxiety and depression. The impact of genetic susceptibility on heart attack risk could be an important factor for cardiologists and general care physicians to consider, Abohashem said.
The researchers are currently working on a study to discover how lifestyle modifications can benefit people with a high genetic risk for stress. As 2024 is an election year, Abohashem advised Americans to manage stress through effective outlets like exercise or yoga. Dr. Laxmi Mehta, an American Heart Association medical expert and cardiology director at The Ohio State University, commented on the study in a statement sent to Fox News Digital.
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