For Patients With Peripheral Artery Disease, Pain Can Be Gain

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For Patients With Peripheral Artery Disease, Pain Can Be Gain
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For people with peripheral artery disease, even short walks can be exercises in excruciation.

"You have to push yourself and get those uncomfortable symptoms, or else you probably won't get gains," said Mary McDermott, MD, professor of medicine at the Feinberg School of Medicine at Northwestern University, Chicago, and the senior author of the study.

McDermott and her colleagues compared 109 people with PAD who walked fast enough to cause discomfort vs 101 people who walked at a comfortable pace and 54 people who did not exercise at all. The average age was 69 years, 48% of participants were women, and 61% were Black. "It's a question that people have asked for some time: Is it necessary to get that ischemic pain when you walk?" McDermott said."This is the first well-powered clinical trial to provide a definitive answer on that, and the answer is that you do need that discomfort. It wasn't even close." Indeed, McDermott said, it's possible that walking merely to the point of comfort and never pushing beyond it may harm people with PAD.

McDermott noted that the nonexercise group was smaller than the discomfort group, making firm comparisons between the two challenging to draw. In addition, people whose exercise was not recorded were not asked to take it easy whenever they walked, unlike those in the comfort group. As a result, she said, some people in this group may have walked vigorously.

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