Removing a patient's tumor while sparing healthy tissue requires exquisite precision, but often surgeons must rely on their eyes and hands to determine where to cut.
Reviewed by Lily Ramsey, LLMOct 16 2023 A team led by researchers from Mass General Brigham has developed a visualization tool that combines high-speed cameras and fluorescent injection to distinguish tumor tissue from normal tissue across cancer types. The team evaluated the new imaging technology, known as fluorescence lifetime imaging, using specimens from more than 60 patients that underwent surgery of various cancers.
Kumar worked closely with colleagues at Mass Eye and Ear, another member of the Mass General Brigham healthcare system, where patients are treated for head and neck cancer. Many technologies have been pursued to improve visualization of tumors during surgery, including fluorescence imaging and advanced microscopy, but such technologies have not yet been widely adopted and most are restricted to specific types or subtypes of cancer.
Building on this initial work, the team collaborated across multiple institutions and evaluated specimens from more than 60 patients representing multiple cancer types, including liver, brain, tongue, skin, bone and soft tissue, who were treated at MGH, Mass Eye and Ear, The University of Pennsylvania, University of Newcastle in the UK, and Leiden University in the Netherlands.
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