Factbox: Global efforts to develop vaccines, drugs to fight the coronavirus

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Factbox: Global efforts to develop vaccines, drugs to fight the coronavirus
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Researchers and drug companies are scrambling to develop vaccines and treatments...

CHICAGO - Researchers and drug companies are scrambling to develop vaccines and treatments to fight the new coronavirus that emerged in central China in December and has spread to more than two dozen countries, killing more than 2,000 people.

Several efforts are using various “plug-and-play” vaccine platforms to develop vaccines using genetic material, RNA or DNA, specific to the virus. In China, officials are trying multiple vaccine candidates, including newer DNA and RNA vaccine approaches and a recombinant protein vaccine in which scientists replicate the proteins on the surface of the virus. Sanofi is using a similar method.To speed access to treatments, researchers are repurposing a number of existing drugs in hope of finding something that works against the new virus.

Gilead Sciences Inc’s remdesivir is an antiviral that failed against Ebola, but has shown promise in monkeys against a related coronavirus. Gilead has partnered with Chinese researchers to conduct two clinical trials coordinated by the China-Japan Friendship Hospital in Beijing. The studies were expected to be completed in April.

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