The metabolic implications of iodine consumption and elucidated the underlying mechanisms.
By Pooja Toshniwal PahariaMar 21 2024Reviewed by Lily Ramsey, LLM In a recent study published in Frontiers in Nutrition, researchers reviewed recent data on the metabolic implications of iodine consumption and elucidated the underlying mechanisms.
Metabolic syndrome , which includes hypertension, abdominal obesity, hyperlipidemia, and hyperglycemia, is common globally and can lead to cardiovascular disease, malignancies, and death. Oxidative stress, chronic inflammatory diseases, and dietary changes are all risk factors for MetS. Cross-sectional research indicates a U-shaped association between urinary iodine concentration and metabolic syndrome prevalence, with a low point of 300 to 499 μg/L.
The TIDE study demonstrated a U-shape curve for the relationship between urinary iodine concentration and diabetes prevalence, with higher UIC levels increasing the likelihood of acquiring diabetes mellitus type 2 . Patients with diabetes mellitus have lower UIC levels than healthy individuals. Mechanisms underlying the metabolic effects of iodine Iodine exerts antioxidative, antimicrobial, immunomodulatory, and molecular regulatory effects. Iodine alters the proportion of pathogenic and beneficial bacteria to restore the gut microbiome and reduce insulin resistance, obesity, and metabolic syndrome parameters.
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