For decades, scientists have searched for an objective and versatile way to measure biological aging, the changes in healthy function over time. This may be it. Via QuantaMagazine
A new tool from Belsky and his colleagues, introduced in 2020 and updated earlier this year, acts as an aging speedometer. In creating theirbiomarker, they quantified the rate of change in 19 markers of organ function at four ages, compiled them into a single index, and modeled it with methylation. “We’re actually quantifying the ongoing process of age-related decline and system integrity,” Belsky said.
in Harare, Zimbabwe, offering him supplies for collecting data from pangolins and several other species. No one even knew for sure how long pangolins live. Some official accounts said 15 to 20 years, but Pietersen thought at least some types live longer. “The one animal that we aged recently was about 34 years old ,” he wrote.
But a clock that merges all of them can help answer a more basic question: What is aging? One view is that your body ages like your shoes, gradually fading and falling apart from wear. But the successful predictions from the pan-mammalian clock imply that something also causes cells to fail on a certain timetable, perhaps because of developmental genes that do not switch off when their work is done.
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