Enhancing Memory With Deep-Brain Stimulation During Sleep

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Enhancing Memory With Deep-Brain Stimulation During Sleep
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Enhancing Memory With Deep-Brain Stimulation During Sleep — Researchers also report fi |

provides the first physiological evidence from inside the human brain supporting the dominant scientific theory on how the brain consolidates memory during sleep. Further, the researchers found that targeted deep-brain stimulation during a critical time in the sleep cycle appeared to improve memory consolidation., could offer new clues for how deep-brain stimulation during sleep could one day help patients with memory disorders likedisease, said study co-author Itzhak Fried, MD, PhD.

The researchers had a unique opportunity to test this theory of memory consolidation via electrodes in the brains of 18 epilepsy patients at UCLA Health. The electrodes had been implanted in the patients’ brains to help identify the source of their seizures during hospital stays typically lasting around 10 days.

Each individual tested performed better on memory tests following a night of sleep with the electrical stimulation compared to a night of undisturbed sleep. Key electrophysiological markers also indicated that information was flowing between the hippocampus and throughout the cortex, providing physical evidence supporting of memory consolidation.

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