Endocannabinoids and the Anti-inflammatory Power of Exercise

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Endocannabinoids and the Anti-inflammatory Power of Exercise
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Understanding why we develop emotional wounds is a start but doesn't make them go away. Here's what needs to happen for true healing to begin, writes tinagilbertson

Exercise Increases Endocannabinoids and Reduces Inflammation

"In the current study we explore the functional interactions between the endocannabinoid system and the gut microbiome in modulating inflammatory markers," the authors explain."So far, no previous study examined the potential link between the endocannabinoid system, exercise, and the gut microbiome."

For this first-of-its-kind research led by Ana Valdes of Nottingham's School of Medicine, the researchers recruited 78 patients with painful osteoarthritis. Study participants were randomly divided into two groups. One cohort participated in a six-week exercise intervention that involved 15-minutes of strength training per day. The control group didn’t exercise.

After six weeks, people in the muscle-strengthening group had higher levels of an endocannabinoid called anandamide along with anti-inflammatory changes in their gut microbiome composition indexed by decreases in the proinflammatory cytokines . Notably, these changes did not occur in the"non-exercise" control group.

According to first author Amrita Vijay, the study shows that exercise increases the body's cannabis-type substances, which has a positive impact. Indeed, simple lifestyle interventions like exercise can modulate endocannabinoids.Amrita Vijay, Afroditi Kouraki, Sameer Gohir, James Turnbull, Anthony Kelly, Vicky Chapman, David A. Barrett, William J. Bulsiewicz & Ana M. Valdes."The Anti-inflammatory Effect of Bacterial Short Chain Fatty Acids Is Partially Mediated by Endocannabinoids.

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