The 22-year-old was driving a Red Vauxhall Corsa which came off the B7078 between Kirkmuirhill and Lesmahagow.
The 22-year-old was driving a Red Vauxhall Corsa which came off the B7078 between Kirkmuirhill and Lesmahagow at about 18:35 on Wednesday.
The road was closed until around 03:30 while police carried out investigations. Officers are appealing for any witnesses toSgt Gemma Blackadder added: "I'd like to thank those members of the public who stopped and helped at the scene, and for those who have already spoken with police."
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