The over-75s, care-home residents and the clinically most vulnerable will be offered the latest Covid booster vaccine
People in those categories who had their last jab more than six months ago will be eligible for the spring booster.is designed to maintain protection for immunosuppressed and elderly people who are at most risk from Covid.
Most people will be offered one of the bivalent vaccines, which targets both the original covid strain and Omicron, the dominant variant for the past 18 months, from either Pfizer/BioNTech or Moderna, or the Sanofi/GSK monovalent jab. The vaccine offered will depend on a person’s age and local supply considerations, the UK Health Security Agency said. Immunosuppressed children under 12 years of age will be offered a children’s formulation of the Pfizer/BioNTech vaccine.
South Africa Latest News, South Africa Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Organ and cell-specific biomarkers of Long-COVID identified with targeted proteomics and machine learning - Molecular MedicineBackground Survivors of acute COVID-19 often suffer prolonged, diffuse symptoms post-infection, referred to as “Long-COVID”. A lack of Long-COVID biomarkers and pathophysiological mechanisms limits effective diagnosis, treatment and disease surveillance. We performed targeted proteomics and machine learning analyses to identify novel blood biomarkers of Long-COVID. Methods A case–control study comparing the expression of 2925 unique blood proteins in Long-COVID outpatients versus COVID-19 inpatients and healthy control subjects. Targeted proteomics was accomplished with proximity extension assays, and machine learning was used to identify the most important proteins for identifying Long-COVID patients. Organ system and cell type expression patterns were identified with Natural Language Processing (NLP) of the UniProt Knowledgebase. Results Machine learning analysis identified 119 relevant proteins for differentiating Long-COVID outpatients (Bonferonni corrected P | 0.01). Protein combinations were narrowed down to two optimal models, with nine and five proteins each, and with both having excellent sensitivity and specificity for Long-COVID status (AUC = 1.00, F1 = 1.00). NLP expression analysis highlighted the diffuse organ system involvement in Long-COVID, as well as the involved cell types, including leukocytes and platelets, as key components associated with Long-COVID. Conclusions Proteomic analysis of plasma from Long-COVID patients identified 119 highly relevant proteins and two optimal models with nine and five proteins, respectively. The identified proteins reflected widespread organ and cell type expression. Optimal protein models, as well as individual proteins, hold the potential for accurate diagnosis of Long-COVID and targeted therapeutics.
Read more »
COVID booster vaccine to be offered to most vulnerableOver 75s and care home residents are among those in England and Wales who will be offered COVID-19 booster jabs this spring, the government has announced.
Read more »
Trial emulation shows the effectiveness of the COVID-19 vaccine in improving long COVID symptomsTrial emulation shows the effectiveness of the COVID-19 vaccine in improving long COVID symptoms univ_spn COVID19 SARSCoV2 LongCOVID Vaccine Effectiveness
Read more »
The true Covid lab leak scandal is how easily our politicians and scientists dismissed itThe true Covid lab leak scandal is how easily our politicians and scientists dismissed it ✒️ ianbirrell for ipaperviews
Read more »
Lancashire's Covid hotspots as one area in Preston records 500% increaseIt's almost three years since the UK was plunged into lockdown
Read more »
Matt Hancock is 'two-faced' and 'was like a headless chicken' during COVID vaccine driveThe former boss of the COVID vaccines taskforce Dr Clive Dix is the latest to take a swipe at the former health secretary, as leaked WhatsApp messages Mr Hancock sent at the height of the pandemic continue to be published by The Daily Telegraph.
Read more »