Welcome to the future where everyone has stores of their own poop lying around the house.
investigating the effect of fecal transplants on conditions ranging from depression to epilepsy and Covid-19 to cancer.
“Genes are what you’re born with, and it is what it is,” says Ong. “But the gut microbiome is something that you can manipulate. And if you can manipulate it to a good outcome in terms of disease, that’s excellent.” There’s just the small matter of finding the right poop, though. In addition to working as a gastroenterologist, Ong cofounded the startup Amili, which has collected more than 1,000 stool samples for transplants over the past three years. However, most willing donors are excluded after filling out questionnaires and having their stool, blood, and saliva tested in the lab.
Lifestyle, diet, medical history—including the use of antibiotics, which can kill off gut bacteria—and how someone was born can all rule people out. In the Norwegian trial, the stool samples used to treat 87 patients with IBS came from one donor: A 36-year-old man who was born vaginally; breastfed; was a nonsmoker; had been treated with antibiotics only a few times; exercised regularly; and consumed high amounts of protein, fiber, minerals, and vitamins.
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