DNA diets are big news at the moment, with personalised nutrition making waves both here and across the pond. But is eating according to our genes really the magic bullet that some would have us believe?
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A Baby With Three People's DNA Has Been Born In The UKMost of the child’s DNA comes from their two parents, but about 0.1% has come from a third person.
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Baby with DNA from three people born in the UKThe scientific technique is designed to prevent children being born with devastating mitochondrial diseases.
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UK's first 'three-parent baby' born after IVF procedureThe procedure is aimed at stopping a mother from passing on defective genes in the mitochondria to her child and involves giving a woman an IVF baby with DNA from three individuals.
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First 'three-parent-baby' born in the UK after IVF procedure developed to prevent children inheriting incurable diseasesA baby has been born using the DNA of three people for the first time in the UK after years of clinical development, the fertility regulator has said.
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EvoAug: improving generalization and interpretability of genomic deep neural networks with evolution-inspired data augmentations - Genome BiologyDeep neural networks (DNNs) hold promise for functional genomics prediction, but their generalization capability may be limited by the amount of available data. To address this, we propose EvoAug, a suite of evolution-inspired augmentations that enhance the training of genomic DNNs by increasing genetic variation. Random transformation of DNA sequences can potentially alter their function in unknown ways, so we employ a fine-tuning procedure using the original non-transformed data to preserve functional integrity. Our results demonstrate that EvoAug substantially improves the generalization and interpretability of established DNNs across prominent regulatory genomics prediction tasks, offering a robust solution for genomic DNNs.
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