Clinical-Grade Pig Kidney Transplanted Into Human Patient in Scientific First

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Clinical-Grade Pig Kidney Transplanted Into Human Patient in Scientific First
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For only the second time ever – and the first involving a clinical-grade organ – a genetically modified pig kidney has successfully been transplanted into a brain-dead human body, in a milestone example of xenotransplantation.

, and the transplant proved these modifications were sufficient to prevent a human body from rejecting the pig's organ in the short term.

No sign of pig cells or pig retroviruses were found in the recipient's blood, and although the tests were limited to just 77 hours in the experiment, transplants of other pig tissues have shown similar resultsWhile the procedure answered many questions, it also highlighted what areas need further investigation. For example, we do not yet know if one pig kidney alone is able to support a human adult, or if two would be required.

While there is still a ways to go yet, this study has also established the safety and feasibility of using brain-dead patients as a model for preclinical research. To honor the recipient and his family, the researchers have proposed calling this"The Parsons Model".

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