A study published in BMCMicrobiol finds that in unvaccinated patients, COVID-19 can induce oral microbial dysbiosis, but oral bacterial diversity is restored with recovery. Research on whether vaccination accelerates recovery of oral microbiome is needed.
]. Our results suggested that oral bacteria and fungi may be involved in recovery from COVID-19. Based on the results of this study, there is potential for the application of microbial-assisted prognosis of COVID-19 patients. In addition, the results presented herein indicated that patients with SARS-CoV-2 infection should be followed from disease onset until after recovery, to thoroughly characterize the profile and the roles of the oral microbiome during SARS-CoV-2 infection.
Our study has several strengths. We first reported the characterization of the oral bacterial and fungal microbiome in patients recovered over 12 months from COVID-19. The previous study only reported several days follow-up of oral and gut microbiota in patients with COVID-19 []. Up to now, there was no reports of oral mycobiome in recovered patients of COVID-19.
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