Case study details a 27-year-old woman with schizoaffective disorder and fibromyalgia who used high-potency cannabis to alleviate pain but experienced adverse psychiatric effects.
By Hugo Francisco de SouzaMay 7 2024Reviewed by Susha Cheriyedath, M.Sc. In a recent study published in the journal Psychiatry Research Case Reports, researchers present the case of a 27-year-old African American woman with a history of schizoaffective disorder suffering from fibromyalgia, a neurological condition characterized by chronic pain .
This case study serves as a warning to cannabis consumers, especially those who are self-medicating despite a family or medical history of psychosis or similar mental health conditions, of our limited current information on the side effects of cannabis consumption and to clinicians of the dangers of cannabis use, especially potent cannabis sources or in high dosages.
Alarmingly, human association-based observational studies and animal psychosis model systems have revealed that high concentrations or amounts of the drug can result in the manifestation or amplification of psychosis, particularly in individuals with a medical or family history of neurological disorders such as schizophrenia.
The intervention lasted one month, at the end of which a follow-up health assessment and questionnaire evaluation was carried out. Conclusions A growing body of literature elucidates the potential role of cannabis, a cocktail of numerous psychoactive compounds, in exacerbating mental health diseases. Specifically, cannabis has been found to have agonistic effects on 5-hydroxytryptamine receptors , transient receptor potential channels of the vanillin subtype , and G protein-coupled receptors while also interacting with NMDA receptors.
Pain Psychosis Anxiety Chronic Chronic Pain Depression Fatigue Fibromyalgia Food Mental Health Psychiatry Receptor Research Schizoaffective Disorder Sleep
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