Can Simparica TRIO Cause Dog Seizures?

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Can Simparica TRIO Cause Dog Seizures?
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In a July 2022 statement emailed to Snopes, Simparica TRIO manufacturer's Zoetis confirmed that the company was 'providing financial support' to the dog's owner.

pamphlet also cautioned against the use of Simparica TRIO in dogs with a history of seizures or neurological disorders:

Snopes contacted Zoetis and was told that the company is “aware of the social media post.” We specifically asked if administration of Simparica TRIO was deemed the cause of Blayz’s death and if the company had agreed to pay for the associated vet bills. We received the statement below: We are confident that Simparica Trio, which has been prescribed to protect over 10 million dogs since coming to the U.S. market in 2020, remains an effective and safe parasite preventative option for most dogs. The overall global reporting rate for any clinical sign reported for Simparica Trio is classified as “very rare”, which is defined by international regulatory authorities as less than 1 report per 10,000 doses administered.

We also reached out to the FDA for further information regarding reporting requirements but have not heard back as of this writing.

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