Multiple lines of research suggest that inflammation in the body can affect the brain and alter mood—a finding that could lead to new solutions for hard-to-treat issues.
Body and brain inflammation have been shown to contribute to deteriorating mental health. But research finds that moving to a cleaner diet, as well as adopting lifestyle changes such as meditation and more exercise, can curb inflammation and improve depression and anxiety. . Depression affects 42 percent of cancer patients, according to the Centers for Diseases Control and Prevention, as many as 42 percent of people withThere is something else those diseases share: inflammation.
Kids who experience abuse and neglect in the first decade of life show elevated levels of several inflammatory molecules by the time they are in their early thirties,. Childhood maltreatment—and chronic inflammation—are also associated with a heightened risk for cardiovascular disease, type 2 diabetes, and other physical health conditions.
Chronic stress activates inflammatory circuits at any age, studies show, but exposure to stress at an early age appears to cause more stubborn forms of depression, Danese says. Identifying the pathways involved provides a window into opportunities to buffer the damaging effects of childhood maltreatment and improve treatments for people with a history of depression.
This x-ray image shows the left knee of a 54-year-old woman with rheumatoid arthritis, an autoimmune disease that attacks the joints, leading to inflammation that causes pain, stiffness, and, in many patients, depression. As in other studies since then, though, the anti-inflammatory only worked as an anti-depressant in people who had elevated levels of inflammation to begin with.
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