Vaccine boosters, as well as breakthrough infections after vaccination, provide substantial immunity against COVID-19, according to a new study.
Vaccine boosters, as well as breakthrough infections after vaccination, provide substantial immunity against COVID-19, according to a In particular, the immune response increased significantly against severe disease, even in ages 65 and older, which could signal a shift in the pandemic, the authors wrote.
The research team analyzed blood samples from 99 OHSU employees after vaccination, including some breakthrough cases. They looked at different aspects of the immune response, such as neutralizing antibodies and those that target the spike protein on the coronavirus. The immune response was also strong against the BA.2 Omicron variant, which was circulating at the time of the study. Researchers said they expect an even more robust immune response among people who receive the new bivalent COVID-19 vaccine this fall that targets the BA.4 and BA.5 variants.
In contrast to the beginning of the pandemic, the coronavirus is no longer"novel" to the human immune system, study authors said. Most people in the world have now been vaccinated, infected, or both, which means people have a more effective immune response than before.
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