Atrial fibrillation (AF) diagnosis was associated with a 45% increased risk of mild cognitive impairment (MCI) among a cohort of 4.3 million individuals in the UK, according to a new study published in JACC: Advances.
Reviewed by Megan Craig, M.Sc.Oct 25 2023 These findings suggest that cardiovascular risk factors and multiple comorbidities could further the progression from MCI to dementia in this cohort.
Our study showed that AF was associated with a 45% increase in the risk of MCI, and that cardiovascular risk factors and multi-comorbidity appear to associate with this outcome." The researchers used the UK primary electronic health record data of 4.3 million individuals to investigate the risk of MCI after AF diagnosis, identifying 233,833 individuals with incident AF and 233,747 without AF.
Related StoriesPatients with AF who were treated with digoxin did not experience an increased MCI risk. The risk of MCI was higher in patients with AF who did not receive oral anticoagulant treatment and amiodarone treatment. Similarly, patients with AF who received oral anticoagulant treatment and amiodarone treatment were not at risk of MCI.
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