Asthma and fine particulate matter | ScienceDaily

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Asthma and fine particulate matter | ScienceDaily
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Drawing on evidence involving about 25 million population worldwide, an international research team demonstrates that long-term exposure to ambient PM2.5 significantly increases the risk of asthma, affecting both children and adults.

The researchers find that approximately 30 percent of new asthma cases worldwide were linked to fine particulate matter exposure, highlighting the dramatic threat air pollution poses to public health.

Typically, the full maturation of lung and immune function is gradually completed until early adulthood. As a result, children may be more susceptible to air pollution exposure, which can lead to airway oxidative stress, inflammation, and hyper-responsiveness, as well as changes in immunological responses and respiratory sensitization to allergens. All these factors play a role in the development of asthma.

The inclusion of evidence from several LMICs mitigates the limitation in approach and enables the exposure-response curves to be applicable to assess city- to global-scale attributable burden of asthma, as well as asthma health benefits associated with air pollution reductions, e.g., health benefits obtained from policy-driven reductions in air pollution under different scenarios.

The study was conducted by researchers from Max Planck Institute for Chemistry , Institute of Atmospheric Physics at the Chinese Academy of Sciences , University of Washington , and Monash University .Long-term exposure to PM2.

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