The presence and severity of anemia in CKD increases markedly with lower eGFRs and is associated with multiple adverse outcomes, a large cohort study has found. MedTwitter
In patients with anemia, iron, as well as vitamin B12, levels were infrequently checked.
"In both men and women with anemia, the prevalence of low iron test results decreased with lower eGFR." Farrington and colleagues report, although low iron test results were more common in women than men, Farrington noted. And somewhat paradoxically, more men and women with higher eGFR levels had low iron test results. For example, in those with anemia and an eGFR of ≥ 90 mL/min/1.73mIn contrast, in those with anemia and an eGFR < 15 mL/min/1.73mAs Farrington explained,portends a better outcome than other common causes of anemia, which are often associated with many other comorbidities.
"Ferritin and iron studies should be checked in all patients with anemia regardless of whether they have CKD or not, and iron deficiency anemia should be treated and evaluated appropriately," she emphasized.
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