An unusual case of Monkeypox virus transmission by needlestick injury Monkeypox Virus Virology HCW hospitalHCFMUSP usp_sao CDC_NCEZID
Research Letter: Monkeypox Virus Transmission to Healthcare Worker through Needlestick Injury, Brazil. Image Credit: FOTOGRIN / Shutterstock
About the study In the present study, researchers described clinical features of MPXV infection in a 20-year-old female nurse after a needlestick injury she sustained on July 9, 2022. The nurse was collecting discardable materials wearing personal protective equipment when a needle perforated her glove; the puncture site was evident immediately. The researchers collected blood, skin lesion samples, and oropharyngeal samples from the infected nurse to test for MPXV deoxyribonucleic acid .
Timeline of symptoms and testing in a case of MPXV transmission to healthcare worker through needlestick injury, Brazil. All collected specimens had RT-PCR detectable MPXV through hospital discharge. Numerals inside squares indicate RT-PCR cycle threshold values. MPXV, monkeypox virus; RT-PCR, reverse transcription PCR.
Concerning the number of skin lesions, the nurse had seven lesions, with three on her face, one on the thumb , right-hand palm, left-hand dorsal side, and left thigh. Magnetic resonance imaging of her injury site on day 15 showed a neurovascular bundle and subcutaneous inflammation. Furthermore, the authors noted that the unusual needlestick MPXV transmission abrogated a prodromal phase in the HCW. It was similar to bite or scratch MPXV transmission from infected animals to humans.
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