Age, Underlying Conditions Top Factors in Breakthroughs

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Age, Underlying Conditions Top Factors in Breakthroughs
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A new analysis found that among fully vaccinated people, the ones most likely to be hospitalized with breakthrough infections of COVID-19 are the elderly and those with specific underlying medical conditions.

Not all breakthrough cases result in hospitalization, but some conditions make it more likely.

Among breakthrough patients with chronic kidney disease, a quarter of them were hospitalized, Truveta said. In comparison, among fully vaccinated people without underlying conditions, only 7.5% of breakthrough cases resulted in hospitalization,The elderly are especially vulnerable to breakthrough cases because old age weakens a person’s immune system.

About 80% of deaths in breakthrough cases are in people 65 and older, The Journal reported, citing data from the. Epic analyzed data from the medical-record software company Epic Systems Corp. The U.S. Centers for Disease Control and Prevention defines a breakthrough case as occurring when a person tests positive at least two weeks after becoming fully vaccinated.

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