Partial resistance to a life-saving antimalarial drug has been detected in Uganda among children experiencing severe forms of the disease.
paint a worrying picture. The authors reported evidence of partial resistance to the antimalarial drug artemisinin among 11 out of 100 children treated for severe malaria at a hospital in Uganda. They found that, for these 11 children, it took longer than expected for the drug to kill the parasites within three days of treatment.
There have been growing concerns about the rise of antimalarial drug resistance spreading across Africa. Resistance develops when the malaria-carrying parasitemutates, allowing the parasite to continue to survive until the drug concentration has reduced. The longer the parasite can stay alive in the body, the higher the chance the treatment can fail. In the case of malaria, this places children with severe malaria at a high risk of death.
Experts have made several recommendations on how to contain the issue. For one, adding another drug to the mix when administering artemisinin can make it trickier for parasites to develop resistance.
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