New mathematicalmodel shows how the body regulates potassium
concentrations in the body within physiological ranges is crucial for proper cell function. The transmembrane Kgradient is a major player in maintaining a proper membrane potential, which helps determine contractility of skeletal and cardiac muscle [intake to extracellular fluid amount is the highest [concentration within a tight normal range is a daily homeostatic challenge because of frequent periods of Kloading and fasting.
Mammals have evolved feedforward and feedback mechanisms to maintain a normal extracellular Kbetween the extra- and intracellular fluids and regulating urinary excretion of KThe model presented in this study includes a comprehensive description of the regulatory mechanisms involved in Khandling. In particular, represented here is the gastrointestinal feedforward control, in which higher dietary Ksecretion.
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