Anime stars some of the craziest mad scientists in fiction, as seen in Soul Eater, Fullmetal Alchemist, and Naruto.
Anime has a penchant for over-the-top characters who bring to the extremes whatever they do, and mad scientists are the perfect expression of this. Over the years, anime have shown some of the most unhinged mad scientists in fiction, as protagonists, supporting characters, and more often villains.
9 Cioccolata - JoJo’s Bizarre Adventure Surgery is a delicate discipline based on thousands of years of medical science. Cioccolata threw all of that in the garbage even before he became an assassin and torturer for Passione. As a doctor, he purposely misdiagnosed patients as needing surgery to get them on his operating table, where he would cut them open with a botched anesthetic so that they could be awake and conscious of the pain.
7 Huey Laforet - Baccano! Writer Ryohgo Narita has created many mad scientist characters, from Szilard Quates to Shinra Kishitani to even Izaya Orihara. However, none of them are quite like Baccano!'s Huey Laforet, whose centuries of life have been wholly dedicated to his sociological and alchemical experiments. Everywhere Huey looks, he doesn’t see other people, only raw materials.
5 Washuu Hakubi - Tenchi Muyo! As beautiful alien women fill his house, Tenchi Masaki learns very quickly that the universe is far stranger than he thought. One of the strangest things in it is Washuu, who is a genius in several fields of science. For twenty thousand years, she has done exactly as she pleases, no matter the consequences, all for the sake of amusing herself.
3 Orochimaru - Naruto Orochimaru’s name is hated and feared throughout the Leaf Village for good reason. Craving immortality, Orochimaru conducted horrific experiments on his fellow villagers. When he was caught and exiled, he only expanded his subject pool, using young shinobi he manipulated into following him and smaller villages he subjugated. His research sinks to the very darkest depths of what Forbidden Jutsu are capable of, and at a terrible cost.
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